Compositions and methods for inhibiting elastase

Details Compositions and methods for inhibiting elastase Compositions and methods for inhibiting elastase

C - Chemistry, Metallurgy

12

N

C12N 9/99 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/78 (2006.01) C07K 14/81 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2108689

2108689 9218141 PCTABS00016 This invention provides a compound comprising: (1) a polypeptide moiety having a) an identifying number of amino acids for SPAAT, b) an elastase binding activity; and (2) an extracellular matrix protein bound to the polypeptide moiety. Also provided is a method of inhibiting an elastase comprising contacting the elastase with a polypeptide moiety having: (1) an identifying number of amino acids for SPAAT; (2) a collagen binding activity; and (3) elastase binding activity.

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