Compositions and methods for inhibiting expression of eg5...

Details Compositions and methods for inhibiting expression of eg5... Compositions and methods for inhibiting expression of eg5...

A - Human Necessities

61

K

A61K 48/00 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2716793

This invention relates to compositions containing double-stranded ribonucleic acid (dsRNA) in a SNALP formulation, and methods of using the compositions to inhibit the expression of the Eg5 and Vascular Endothelial Growth Factor (VEGF), and methods of using the compositions to treat pathological processes mediated by Eg5 and VEGF expression, such as cancer.

La présente invention concerne des compositions contenant de lacide ribonucléique double brin (dsRNA) dans une formulation SNALP et des procédés dutilisation des compositions pour inhiber lexpression de lEg5 et du facteur de croissance endothélial vasculaire (VEGF), ainsi que des procédés dutilisation des compositions pour traiter des processus pathologiques provoqués par lexpression dEg5 et de VEGF, comme le cancer.

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