Compositions and methods for inhibiting g protein signaling

Details Compositions and methods for inhibiting g protein signaling Compositions and methods for inhibiting g protein signaling

A - Human Necessities

61

K

A61K 38/17 (2006.01)

Patent

CA 2600946

The present invention relates to methods for identifying agents which bind to specific amino acid residues of the protein interaction site of G protein .beta. subunit. Compounds identified in accordance with the assay of the invention and methods for using the compound for modulating at least one activity of a G protein are also provided.

L'invention concerne des procédés destinés à identifier des agents qui se lient à des résidus d'acides aminés spécifiques du site de réaction de protéine d'une sous-unité .beta. de protéine G. Les composés identifiés selon le dosage de l'invention et des procédés utilisant le composé en vue de moduler au moins une activité d'une protéine G sont également décrits.

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