Compositions and methods for inhibiting growth or...

Details Compositions and methods for inhibiting growth or... Compositions and methods for inhibiting growth or...

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2092711

2092711 9205284 PCTABS00011 The invention relates to compositions and methods for inhibiting the growth or replication of microbes, viruses or self-replicating nucleic acids. Antisense oligonucleotides that bind to strategic sites in the microbe, virus of self-replicating nucleic acid genome find particular utility in preventing proliferation and pathogenesis; and in detecting microbe, virus or self-replicating nucleic acid. Therapeutic compositions comprising at least two oligonucleotides and methods using the compositions are effective in inhibiting the growth or replication of homologous and heterologous microbes, viruses or self-replicating nucleic acids.

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