Compositions and methods for liver growth and liver protection

Details Compositions and methods for liver growth and liver protection Compositions and methods for liver growth and liver protection

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/00 (2006.01) A61K 38/00 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) A61P 1/16 (2006.01) C07K 14/475 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/00 (2006.01) C12N 15/85 (2006.01) C12N 15/88 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2486270

The present invention provides pharmaceutical compositions and methods for liver proliferation and protection. Specifically useful are VEGFR modulating agents capable of promoting liver growth. Disclosed compositions and methods may be useful for promoting proliferation or treating pathological conditions in other organs of significant biological functions.

L'invention concerne des compositions pharmaceutiques ainsi que des méthodes de régénération et de protection du foie. Plus particulièrement, l'invention fait intervenir des agents de modulation du facteur de croissance vasculaire endothéliales (VEGFR) qui sont capables d'activer la croissance du foie. Les compositions et les méthodes de l'invention peuvent servir à activer la régénération ou à traiter des états pathologiques dans d'autres organes qui remplissent d'importantes fonctions biologiques.

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