A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01)
Patent
CA 2503763
The present invention provides methods to produce immunotoxins (ITs) and cytokines with a reduced ability to promote vascular leak syndrome (VLS). The invention also provides Its and cytokines which have been mutated to lack amino acid sequences which induce VLS.
La présente invention concerne des procédés pour produire des immunotoxines (IT) et des cytokines qui ont une aptitude réduite à favoriser le syndrome de perte vasculaire (VLS). L'invention a également pour objet des It et des cytokines qui ont été mutées pour ne plus contenir de séquences d'acides aminés qui provoquent le VLS.
Baluna Roxana G.
Ghetie Victor F.
Smallshaw Joan
Vitetta Ellen S.
Board Of Regents The University Of Texas System
Kirby Eades Gale Baker
LandOfFree
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