A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4709 (2006.01) A61K 31/49 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2561993
The present application relates to compositions which modulate the activity of gated ion channels. This provide an effect in the treatment of pain, inflammatory disorders and neurological disorders. Preferred compounds include quinine or quinidine derivatives with the hydroxyl at the nine position being esterified with an aliphatic carboxylic acid, optionally bearing an additional cycloalkyl ring on the chain. The gated ion channels modulated include homomultimeric and heteromultimeric gates.
La présente invention concerne des compositions et des méthodes de modulation de l'activité des canaux ioniques commandés par porte.
Ahring Philip K.
Babinski Kazimierz
Blackburn-Munro Gordon John
Dyhring Joergensen Tino
Szarek Walter A.
Gowling Lafleur Henderson Llp
Painceptor Pharma Corporation
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