Compositions and methods for modulating inflammation using...

A - Human Necessities – 61 – K

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A61K 31/55 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2686833

Compositions for modulating an inflammation comprise a fluoroquinolone having one of Formulae I- VIII. Methods for modulating an inflammation comprise administering such compositions to a subject in need thereof. The compositions and methods are suitable for modulating an ocular or ophthalmic inflammation, including uveitis, vernal keratoconjunctivitis, or inflammation associated with contact lens-associated corneal infiltrates.

La présente invention concerne des compositions destinées à moduler une inflammation qui renferment une fluoroquinolone ayant l'une des formules I à VIII. Les procédés de modulation d'une inflammation comprennent l'administration de telles compositions à un sujet en ayant besoin. Les compositions et les procédés sont appropriés pour moduler une inflammation oculaire ou ophtalmique, y compris une uvéite, une kératoconjonctivite printanière ou une inflammation liée à des infiltrats cornéens associés aux lentilles de contact.

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