Compositions and methods for modulating retinol binding to...

Details Compositions and methods for modulating retinol binding to... Compositions and methods for modulating retinol binding to...

C - Chemistry, Metallurgy

07

D

C07D 261/08 (2006.01) A61K 31/42 (2006.01) A61K 31/421 (2006.01) A61K 31/4245 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61P 27/02 (2006.01) C07D 263/32 (2006.01) C07D 271/06 (2006.01) C07D 277/30 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2758587

The present invention relates to compositions and methods for modulating retinol binding to retinol binding protein 4(RBP4). In particular, the present invention provides compounds having Formula (1) or (2) (Formulae (1), (2)); wherein R1, R2, R3, R4, R5, R6, Y1, Y2, Y3, Y4 and m are as defined above.

La présente invention porte sur des compositions et des procédés permettant de moduler la liaison du rétinol à la protéine 4 de liaison au rétinol (RBP4). En particulier, la présente invention porte sur des composés représentés par la Formule (1) ou (2) (Formules (1), (2)) ; dans lesquelles R1, R2, R3, R4, R5, R6, Y1, Y2, Y3, Y4 et m sont tels que définis ci-dessus.

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