Compositions and methods for prolonging survival of platelets

Details Compositions and methods for prolonging survival of platelets Compositions and methods for prolonging survival of platelets

A - Human Necessities

01

N

A01N 1/02 (2006.01) A61K 35/14 (2006.01)

Patent

CA 2499463

The present invention provides modified platelets having a reduced platelet clearance and methods for reducing platelet clearance. Also provided are compositions for the preservation of platelets. The invention also provides methods for making a pharmaceutical composition containing the modified platelets and for administering the pharmaceutical composition to a mammal to mediate hemostasis.

La présente invention concerne des plaquettes modifiées présentant une clairance de plaquettes réduite, et des méthodes de réduction de la clairance des plaquettes. L'invention concerne également des compositions pour la préservation des plaquettes. L'invention concerne en outre des méthodes de fabrication d'une composition pharmaceutique contenant les plaquettes modifiées, et d'administration de la composition pharmaceutique à un mammifère pour la médiation de l'hémostase.

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