A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/10 (2006.01) A61P 7/04 (2006.01)
Patent
CA 2609656
Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaiminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.
L'invention porte sur des compositions qui comprennent des substances structurées à une nanoéchelle ou des précurseurs de celles-ci (tels que des peptides d'auto-assemblage). L'invention porte également sur des méthodes d'utilisation des compositions visant à favoriser l'hémostase, protéger la peau ou les plaies de la contamination et décontaminer un site lors de l'élimination des compositions précédemment appliquées qui ont formé un revêtement protecteur, et inhiber le déplacement des substances biologiques autres que le sang. Les compositions sont également utiles pour isoler, retirer et conserver des tissus (par exemple, pour une transplantation ou une refixation ultérieure) et comme agents de gonflement, de stabilisation ou d'hydratation. L'invention porte également sur des dispositifs médicaux comprenant les compositions (tels qu'une endoprothèse vasculaire ou cathéter), des bandages ou autres pansements, des sutures et sur des kits comprenant les compositions de l'invention.
Ellis-Behnke Rutledge
Liang Yu-Xiang
Schneider Gerald
So Kwok-Fai
Tay David
Cassan Maclean
Massachusetts Institute Of Technology
Versitech Limited
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