Compositions and methods for pulmonary gene delivery

Details Compositions and methods for pulmonary gene delivery Compositions and methods for pulmonary gene delivery

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61M 15/00 (2006.01)

Patent

CA 2265838

Compositions and methods are provided for gene delivery to the respiratory tract. In particular, compositions comprising a nebulized nucleic acid/stabilizing agent complex, and methods employing such complexes for pulmonary gene delivery, are provided. Such complexes are preferably sonic nebulized.

L'invention porte sur des compositions et des procédés de libération de gènes dans les voies respiratoires. Elle porte plus particulièrement sur des compositions contenant un complexe acide nucléique/agent stabilisant en aérosol et sur des procédés dans lesquels on utilise ces complexes pour libérer des gènes dans les voies respiratoires. De tels complexes se présentent de préférence sous forme d'aérosols soniques.

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