Compositions and methods for re-programming cells without...

C - Chemistry – Metallurgy – 07 – K

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C07K 19/00 (2006.01) C12N 5/071 (2010.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07K 14/47 (2006.01) C07K 17/00 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2748009

The present inventions are directed to compositions and methods regarding the reprogramming of biological samples (such as cells) without introducing exogenous genes to the samples. In particular, the present inventions are directed to transducible materials that are capable of transducing into the biological samples but are not genes or causing genetic modifications. The present inventions also are directed to methods of reprogramming the path of biological samples or treating diseases using the tranducible compositions thereof.

La présente invention concerne des compositions et des procédés relatifs à la reprogrammation d'échantillons biologiques tels que des cellules sans introduire de gènes exogènes dans lesdits échantillons. L'invention concerne en particulier des matériaux transducteurs capables de pénétrer par transduction dans les échantillons biologiques, lesdits matériaux n'étant cependant pas des gènes et ne causant aucune modification génétique. Cette invention concerne aussi des procédés visant à reprogrammer la voie d'échantillons biologiques ou à traiter des maladies à l'aide desdites compositions transductrices.

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