A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/496 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01)
Patent
CA 2257393
The present invention relates to diarylmethyl piperazine compounds and diarylmethyl piperidine compounds, and pharmaceutical compositions thereof, having utility in medical therapy especially for reducing respiratory depression associated with certain analgesics, such as mu opiates. This invention additionally relates to diarylmethyl piperazine compounds and diarylmethyl piperidine compounds having utility in assays for determining the respiratory reducing characteristics of other bioactive compounds, including other diarylmethyl piperazine compounds and other diarylmethyl piperidine compounds.
La présente invention concerne des composés diarylméthyl pipérazine et des composés diarylméthyl pipéridine, et leurs compositions pharmaceutiques, qui sont utiles en thérapie et notamment pour réduire la dépression respiratoire associée à certains analgésiques tels que des opiacés mu. Cette invention concerne de plus des composés de diarylméthyl pipérazine et des composés de diarylméthyl pipéridine qui sont utilisés dans des dosages afin de déterminer les caractéristiques de réduction respiratoire d'autres composés bioactifs tels que d'autres composés de diarylméthyl pipérazine et diarylméthyl pipéridine.
Bishop Michael J.
Chang Kwen-Jen
Mcnutt Robert W. Jr.
Pettit Hugh O.
Delta Pharmaceuticals Inc.
Kirby Eades Gale Baker
Mount Cook Biosciences Inc.
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