C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 5/06 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2388517
This invention relates to methods and compositions for the treatment of tumors. In particular, the invention relates to methods and agents for the treatment of tumors expressing a tumor-antigen [also known as a tumor- associated antigen (TAA), lineage specific, differentiation, or self- antigens], and more specifically to methods and agents for the treatment of melanomas expressing the Melan-A/MART-1 antigen. The invention also relates to methods for identifying agents that regulate expression of tumor-antigens.
L'invention concerne des méthodes et des compositions destinées au traitement de tumeurs. L'invention concerne en particulier des méthodes et des agents destinés au traitement de tumeurs qui expriment un antigène tumoral [également appelé antigène spécifique de tumeurs (TAA), antigène spécifique de lignée, antigène de différentiation ou autoantigène] et plus particulièrement des méthodes et des agents destinés au traitement de mélanomes qui expriment l'antigène Melan-A/MART-1. L'invention concerne également des méthodes permettant d'identifier des agents qui régulent l'expression des antigènes tumoraux.
Durda Paul J.
Kurnick James T.
Smart & Biggar
The General Hospital Corporation
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