Compositions and methods for regulation of tumor necrosis...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/24 (2006.01) A61K 38/20 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07K 14/54 (2006.01) C07K 16/24 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2545359

The present invention relates to compositions and methods relating to an interleukin~18- inducible cytokine termed tumor necrosis factor-alpha inducing factor (TAIF) or interleukin-32 (IL-32). In particular, the present invention provides compositions and methods for treating autoimmune diseases and cancer, in part by regulation of tumor necrosis factor-alpha expression.

La présente invention se rapporte à des compositions et à des procédés liés à une cytokine inductible par l'interleukine-18 dénommée facteur induisant le facteur-alpha de nécrose tumorale (TAIF) ou interleukine-32 (IL-32). En particulier, la présente invention se rapporte à des compositions et à des procédés de traitement de maladies auto-immunes et du cancer, notamment par régulation de l'expression du facteur-alpha de nécrose tumorale.

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