A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/44 (2006.01) A61K 31/4412 (2006.01) A61K 31/443 (2006.01) A61K 31/4436 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01)
Patent
CA 2161648
In a preferred embodiment, drugs having phar- macological properties which are useful in the medic- inal therapy of fibrotic disease for the reparation and prevention of fibrotic lesional tissues, such drugs including as active ingredient(s) one or more N- substituted 2-(1H) pyridone(s) and/or N-substituted 3- (1H) pyridones. The composition of this invention is novel as an anti-fibrotic drug, namely, as an agent for treating fibrosis. Any existing compounds have not been shown to be effective for the reparation and prevention of fibrotic lesions. The figure is a graphic representation of a response to a dosage of pirfenidone as shown in Table 3.
Margolin Solomon B.
Osler Hoskin & Harcourt Llp
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