A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/49 (2006.01) C12N 9/70 (2006.01) C12N 9/72 (2006.01) C12N 9/96 (2006.01)
Patent
CA 2530529
Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots, which are capable of selective dissolution of pathological nascent clots formed intravascularly, with minimal risk of unwanted dissolution of pre-existing hemostatic clots, are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers.
L'invention concerne des compositions et des méthodes destinées à prévenir et traiter la formation incontrôlée de caillots de fibrine intravasculaires, et permettant une dissolution sélective de caillots pathologiques naissants formés de manière intravasculaire avec un risque minimal de dissolution indésirable des caillots hémostatiques préexistants. Selon l'invention, des médicaments fibrinolytiques ou anticoagulants sont couplés de manière biocompatible à des supports de globules rouges.
Cines Douglas
Murciano Juan Carlos
Muzykantov Vladimir R.
Borden Ladner Gervais Llp
The Trustees Of The University Of Pennsylvania
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