A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 39/015 (2006.01) A61K 39/04 (2006.01) A61K 39/118 (2006.01)
Patent
CA 2572985
The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating glycolipids into the liposomes. The stabilized liposomes can be used either as an adjuvant for antigenic components or as a drug delivery system. In particular the invention relates to vaccines with adjuvants in aqueous media for immunization, where the final product is stable.
La présente invention concerne des formulations de liposomes qui sont physiquement stables. Cette invention se rapporte plus particulièrement à la stabilisation stérique de liposomes cationiques au moyen de l'incorporation de glycolipides dans les liposomes. Les liposomes stabilisés peuvent être utilisés soit en tant qu'adjuvant pour des constituants antigéniques soit en tant que système d'apport de médicament. Cette invention concerne plus spécifiquement des vaccins comprenant des adjuvants dans un milieu aqueux qui sont destinés à l'immunisation, le produit final obtenu étant stable.
Andersen Peter
Davidsen Jesper
Rosenkrands Ida
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Statens Serum Institut
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