Compositions and methods for stimulating an immune response...

A - Human Necessities – 61 – K

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A61K 39/145 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2388054

The invention provides for oral compositions for safely stimulating an immune response to mucoadhesive antigens for protection against infectious agents, particularly influenza viruses using heat-labile, mutant Escherichia coli enterotoxins and antigen. Methods of stimulating immune responses and for eliciting IgA antibodies are also provided.

L'invention concerne des compositions orales destinées à stimuler de façon sûre une réponse immune aux agents mucoadhésifs pour former une protection contre les agents infectieux, en particulier les virus de la grippe, utilisant des entérotoxines thermolabiles mutantes d'Escherichia coli et un antigène. L'invention concerne également des méthodes destinées à stimuler les réponses immunes et à produire des anticorps IgA.

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