C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 255/02 (2006.01) A61K 31/395 (2006.01) A61P 31/18 (2006.01) A61P 33/06 (2006.01) C07D 273/02 (2006.01) C07D 273/06 (2006.01) C07D 285/38 (2006.01)
Patent
CA 2635359
Methods for the synthesis of various novel substituted dipeptide derived nitrogen-containing heterocyclic compounds (I) and their pharmaceutically acceptable salt derivatives are provided. The compounds of the invention are claimed and are useful as medicaments for the treatment or prevention of disease in a mammal, for example a human. In particular the compounds are useful as immuno therapeutics and anti -microbial drugs or vaccines. These heterocyclic derivatives can be used as an active agent in a pharmaceutical, as well as a diagnostic utility.
L'invention concerne des méthodes destinées à la synthèse de divers nouveaux composés hétérocycliques (I) contenant de l'azote dérivés de dipeptides substitués ainsi que leurs dérivés de sels de qualité pharmaceutique. Ces composés sont utiles comme médicaments pour le traitement ou la prévention d'une maladie chez un mammifère, tel qu'un être humain. Plus particulièrement, ces composés sont utiles comme agents immunothérapeutiques et comme médicaments ou vaccins antimicrobiens. Ces dérivés hétérocycliques peuvent être utilisés comme un agent actif à des fins pharmaceutiques et diagnostiques.
Guichard Gilles
Lallemand Eliette
Lena Gersande
Renia Laurent
Centre National de La Recherche Scientifique (cnrs)
Fetherstonhaugh & Co.
Immupharma France Sa
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