Compositions and methods for systemic administration of...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 31/711 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61P 19/08 (2006.01) C07K 14/51 (2006.01)

Patent

CA 2449008

Compositions and methods for systemic administration of DNA encoding bone morphogenic proteins for promotion of osteogenesis are disclosed. The compositions and methods of the invention may be utilized for fracture repair. The invention further discloses compositions and methods for systemic administration of bone morphogenetic proteins for promotion of osteogenesis. These compositions and methods may be used in bone fracture healing and repair. These composition of the invention may be further utilized in increasing bone mineral density.

L'invention concerne des compositions et des méthodes pour l'administration systémique d'ADN codant pour les protéines morphogénétiques osseuses afin de stimuler l'ostéogenèse. Ces compositions et ces méthodes peuvent convenir pour la réparation des fractures. L'invention concerne également des compositions et des méthodes pour l'administration systémique de protéines morphogénétiques osseuses afin de stimuler l'ostéogenèse. Ces compositions et ces méthodes peuvent convenir pour la réparation et la guérison des fractures osseuses ainsi que pour l'accroissement de la densité minérale osseuse.

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