Compositions and methods for taxol biosynthesis

Details Compositions and methods for taxol biosynthesis Compositions and methods for taxol biosynthesis

C - Chemistry, Metallurgy

12

N

C12N 15/60 (2006.01) C12N 9/88 (2006.01) C12N 9/90 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2250693

The taxadiene synthase gene of Pacific new has been cloned and its nucleic acid and polypeptide sequence is presented. Truncation or removal of the transit peptide increases expression of the cloned taxadiene synthase gene expression in E. coli cells.

Le gène de la taxadiène synthétase de l'if occidental a été cloné et sa séquence nucléotidique et polypeptidique est présentée. La troncature ou l'élimination du peptide de transit augmente l'expression du gène de la taxadiène synthétase cloné dans les cellules d'E. coli.

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