C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01)
Patent
CA 2445991
Compositions and methods of detecting biomarkers associated with cardiovascular disease through the use of cardiac tissue microarrays are provided. The compositions of the present invention comprise a human cardiovascular tissue microarray comprising a plurality of tissues derived from at least one human donor, and reflecting at least one state of cardiovascular disease. The methods of the present invention comprise treating a human cardiovascular tissue microarray under conditions such that a biomarker associated with cardiovascular disease is detected.
Cette invention se rapporte à des compositions et à des procédés servant à détecter les biomarqueurs associés à une maladie cardio-vasculaire grâce à l'utilisation de jeux ordonnés de microéchantillons de tissus cardiaques. Ces compositions comprennent un jeu ordonné de microéchantillons de tissus cardio-vasculaires humains composés de plusieurs tissus dérivés d'au moins un donneur humain et reflétant un état de la maladie cardio-vasculaire. Ces procédés consistent à traiter un jeu ordonné de microéchantillons de tissus cardio-vasculaires humains dans des conditions telles que le biomarqueur associé à la maladie cardio-vasculaire soit détecté.
Genero Mario Hugo
Ojeda Elizabeth Edit
Genomics Ltd.
Smart & Biggar
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