C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/38 (2006.01) A61K 38/16 (2006.01) A61K 39/245 (2006.01) A61P 31/22 (2006.01) C07K 14/035 (2006.01) C07K 16/08 (2006.01) C12N 15/62 (2006.01) G01N 33/571 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2411692
Compounds and methods for the diagnosis and treatment of HSV infection are provided. The compounds comprise polypeptides that contain at least one antigenic portion of an HSV polypeptide and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits are also provided comprising such polypeptides and/or DNA sequences and a suitable detection reagent for the detection of HSV infection in patients and in biological samples.
L'invention concerne des composés et des méthodes de diagnostic et de traitement de l'infection du virus de l'herpès. Ces composés comprennent des polypeptides contenant au moins une partie antigénique d'un polypeptide du virus de l'herpès et des séquences d'ADN codant pour ces polypeptides. L'invention concerne également des compositions pharmaceutiques et des vaccins comprenant ces polypeptides ou séquences d'ADN, ainsi que des anticorps dirigés contre ces polypeptides. L'invention concerne enfin des kits de diagnostic comprenant ces polypeptides et/ou séquences d'ADN et un réagent de détection approprié servant à détecter une infection du virus de l'herpès chez des patients et dans des échantillons biologiques.
Day Craig H.
Dillon Davin C.
Hosken Nancy A.
Mcgowan Patrick
Sleath Paul R.
Corixa Corporation
Gowling Lafleur Henderson Llp
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