A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/12 (2006.01) A61K 39/245 (2006.01) C07K 14/035 (2006.01) C12P 19/34 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2481087
Compounds and methods for the diagnosis and treatment of HSV infection are provided. The compounds comprise polypeptides that contain at least one antigenic portion of an HSV polypeptide and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits are also provided comprising such polypeptides and/or DNA sequences and a suitable detection reagent for the detection of HSV infection in patients and in biological samples.
L'invention porte sur des composés et des procédés pour le diagnostic et le traitement de l'infection HSV. Ces composés comprennent des polypeptides qui contiennent au moins une partie antigène d'un polypeptide HSV et des séquences ADN qui codent ces polypeptides. L'invention concerne aussi des compositions pharmaceutiques et des vaccins comprenant ces polypeptides ou séquences ADN, ainsi que des anticorps contre les polypeptides en question. L'invention se rapporte également à des trousses de diagnostic comprenant ces polypeptides et/ou séquences ADN et un réactif de détection convenable pour la détection de l'infection HSV chez les patients et dans des échantillons biologiques.
Day Craig H.
Hosken Nancy A.
Parsons Joseph M.
Corixa Corporation
Gowling Lafleur Henderson Llp
LandOfFree
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