C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C12N 15/00 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2323833
This invention provides compositions and methods for the identification of lung cancer cells. In particular, polynucleotide sequences whose presence is indicative of lung cancer are disclosed. In addition, lung cancer can be identified by detecting the presence of the peptides encoded by these sequences. Antibodies to these peptides are also provided. Also included are gene delivery vehicles and host cells comprising these polynucleotides. Kits containing agents and instructions necessary to perform the screening and detecting methods are also provided.
La présente invention concerne des compositions et méthodes d'identification de cellules de cancer du poumon. L'invention concerne en particulier des séquences polynucléotidiques dont la présence indique un cancer du poumon. En outre, on peut identifier un cancer du poumon en détectant la présence des peptides codés par ces séquences. L'invention concerne également des anticorps contre ces peptides, ainsi que des véhicules de fourniture de gènes et des cellules hôtes comprenant ces polynucléotides. L'invention concerne enfin des trousses contenant des agents et des instructions nécessaires à l'application des méthodes de criblage et de détection.
Beaudry Gary A.
Bertelsen Arthur H.
Madden Stephen L.
Genzyme Corporation
Gowling Lafleur Henderson Llp
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