Compositions and methods for the prevention and diagnosis of...

Details Compositions and methods for the prevention and diagnosis of... Compositions and methods for the prevention and diagnosis of...

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/02 (2006.01) A61K 39/295 (2006.01) A61K 39/385 (2006.01) A61K 39/395 (2006.01) C07K 14/20 (2006.01) C07K 16/12 (2006.01) C07K 19/00 (2006.01) C12N 5/18 (2006.01) C12N 15/12 (2006.01) C12N 15/51 (2006.01) C12N 15/62 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2084413

2084413 9200055 PCTABS00010 Methods and compositions for the prevention and diagnosis of Lyme disease. OspA and OspB polypeptides and serotypic variants thereof, which elicit in a treated animal the formation of an immune response which is effective to treat or protect against Lyme disease as caused by infection with B. burgdorferi. Anti-OspA and anti-OspB antibodies that are effective to treat or protect against Lyme disease as caused by infection with B. burgdorferi. A screening method for the selection of those OspA and OspB polypeptides and anti-OspA and anti-OspB antibodies that are useful for the prevention and detection of Lyme disease. Diagnostic kits including OspA and OspB polypeptides or antibodies directed against such polypeptides.

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