Compositions and methods for the storage of red blood cells

Details Compositions and methods for the storage of red blood cells Compositions and methods for the storage of red blood cells

A - Human Necessities

01

N

A01N 1/00 (2006.01) A01N 1/02 (2006.01) A61K 35/18 (2006.01)

Patent

CA 2598366

The present invention provides an aqueous composition for storage of red blood cells consisting essentially of: adenine; dextrose; at least one non- metabolizable membrane-protectant sugar; and a specifically defined pH buffering system. Also provided are improved methods for preserving red blood cells and methods for increasing the viability, membrane retention, and recoverability while suppressing apoptosis, hemolysis, and post-reinfusion clearance of stored red blood cells which utilize the novel compositions.

La présente invention propose une composition aqueuse destinée au stockage des globules rouges consistant sensiblement en : adénine ; dextrose ; au moins un sucre protecteur de membrane non métabolisable ; et un système de tampon de pH spécifiquement défini. L~invention propose également des procédés améliorés destinés à conserver les globules rouges et des procédés destinés à augmenter la viabilité, la rétention membranaire et l~aptitude à la récupération tout en supprimant l~apoptose, l~hémolyse et la clairance de post-réinfusion des globules rouges stockés qui utilisent les nouvelles compositions.

Affiliated with

Also associated with

Rating

Compositions and methods for the storage of red blood cells does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for the storage of red blood cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for the storage of red blood cells will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2066140