Compositions and methods for the systemic treatment of...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/04 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2557508

The present invention includes compositions and methods for treating arthritic joints found in patients with autoinflammation, e.g., systemic onset juvenile idiopathic arthritis, by administering at the site of inflammation a therapeutically effective amount of at least one agent that reduces or blocks the bioavailability of interleukin-1.beta..

La présente invention concerne des compositions et des méthodes de traitement des articulations arthritiques rencontrées chez des patients présentant une auto-inflammation, par exemple de l'arthrite idiopathique systémique juvénile constatée, par administration sur le site de l'inflammation d'une dose thérapeutique efficace d'au moins un agent réduisant ou bloquant la biodisponibilité de l'interleukine-1.beta..

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