C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/11 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2397741
Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
L'invention concerne des compositions et des méthodes destinées au traitement et au diagnostique de cancer, plus précisément le cancer de la prostate. Ces compositions comprennent un ou plusieurs polypeptides spécifiques de la prostate, des portions immunogéniques de ces polypeptides, des polynucléotides codant pour ces polypeptides, une cellule présentant un antigène qui exprime ces polypeptides, et des cellules T qui sont spécifiques des cellules exprimant ces polypetides. Les compositions selon l'invention conviennent, par exemple, pour le diagnostique, la prévention et/ou le traitement de maladies, notamment le cancer de la prostate.
Day Craig H.
Dillon Davin C.
Fanger Gary Richard
Harlocker Susan L.
Jiang Yuqiu
Corixa Corporation
Gowling Lafleur Henderson Llp
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