C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2576940
Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly cervical cancer.
La présente invention a trait à des compositions et des procédés pour la thérapie et le diagnostic du cancer, notamment du cancer du poumon. Des compositions représentatives comportent un ou des polypeptides de tumeur pulmonaire, des portions immunogènes de ceux-ci, des polynucléotides codant pour de tels polypeptides, une cellule présentatrice de l'antigène exprimant de tels polypeptides, et des lymphocytes T qui sont spécifiques pour des cellules exprimant de tels polypeptides. Les compositions de l'invention sont utiles, par exemple, dans le diagnostic, la prévention et/ou le traitement de maladies, notamment le cancer du col de l'utérus.
Bangur Chaitanya S.
Zehentner-Wilkinson Barbara K.
Borden Ladner Gervais Llp
Corixa Corporation
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