A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/7036 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 9/12 (2006.01) C12N 9/80 (2006.01) G01N 33/68 (2006.01) G01N 33/92 (2006.01)
Patent
CA 2432978
Methods and compositions are disclosed that are useful for the prevention and/or treatment of cardiovascular and cardiac diseases and disorders, or damage resulting from surgical or medical procedures that may cuase ischemic or ischemic/reperfusion damage in humans; and cardiovascular trauma. The beneficial effects of the compositions and methods are achieved through the use of pharmaceutical compositions that include agents that interfere with the production and/or biological activities of sphingolipids and their metabolites, particularly sphingosine (SPH) and sphingosine-1-phosphate (S-1- P). Also disclosed are methods for identifying and isolating therapeutic agents.
L'invention concerne des procédés et des compositions utiles pour la prévention et/ou le traitement de troubles et de maladies cardiaques et cardio-vasculaires, ou de dommages résultant de procédures chirurgicales ou médicales qui peuvent provoquer une ischémie, ou un blessure ischémique due à une perfusion, et une lésion cardio-vasculaire chez l'homme. Les effets bénéfiques des compositions et des procédés sont réalisés à l'aide de compositions pharmaceutiques comprenant des agents qui interfèrent avec la production et/ou les activités biologiques des sphingolipides et de leurs métabolites, en particulier de la sphingosine (SPH) et de la sphingosine-1-phosphate (S-1-P). L'invention concerne aussi des procédés d'identification et d'isolement d'agents thérapeutiques.
Gowling Lafleur Henderson Llp
Medlyte Inc.
LandOfFree
Compositions and methods for the treatment and prevention of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and methods for the treatment and prevention of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for the treatment and prevention of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1930132