A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61K 9/02 (2006.01) A61K 9/06 (2006.01) A61K 31/04 (2006.01) A61K 31/137 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/21 (2006.01) A61K 31/34 (2006.01) A61K 31/4015 (2006.01) A61K 31/4245 (2006.01) A61K 31/472 (2006.01) A61K 31/517 (2006.01) A61K 31/522 (2006.01) A61K 31/565 (2006.01) A61K 38/00 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P 1/00 (2006.01) A61P 9/14 (2006.01) A61P 17/04 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2354543
Compositions and methods for the treatment of anorectal disorders are provided in which certain combinations of NO donors, PDE inhibitors, superoxide (O2-) scavengers, .beta.-adrenergic agonists, cAMP-dependent protein kinase activators, .alpha.1-adrenergic antagonists, L-type Ca2+ channel blockers, estrogens, ATP-sensitive K+ channel activators and smooth muscle relaxants are used.
L'invention concerne des compositions et des techniques conçues pour le traitement de troubles anorectaux. Certaines combinaisons sont utilisées: donneurs de NO, inhibiteurs de la PDE, capteurs de superoxydes (O¿2??-¿), agonistes .beta.-adrénergiques, activateurs de protéine kinase dépendante de cAMP, antagonistes .alpha.¿1?-adrénergiques, bloqueurs de canal Ca?2+¿ de type L, oestrogènes, activateurs de canal K?+¿ dépendant de l'ATP et relaxants musculaires doux.
Lee Charles
Lee Jung-Chung
Mak Vivien
Parks Thomas P.
Cellegy Pharmaceuticals Inc.
Fetherstonhaugh & Co.
Strakan International Limited
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