A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/52 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/335 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/522 (2006.01) A61K 31/554 (2006.01)
Patent
CA 2417848
Compositions and methods for the treatment of anorectal disorders are provided in which certain combinations of NO donors, PDE inhibitors, superoxide (O2-) scavengers, .beta.-adrenergic agonists, cAMP-dependent protein kinase activators, .alpha.1-adrenergic antagonists, L-type Ca2+ channel blockers, estrogens, ATP-sensitive + channel activators and smooth muscle relaxants are used.
L'invention concerne des compositions et des méthodes destinées au traitement des troubles anorectaux, consistant à utiliser certaines combinaisons: donneurs de NO, inhibiteurs de la PDE, capteurs de superoxydes (O2-), agonistes .beta.-adrénergiques, activateurs de la protéine kinase dépendante de cAMP, antagonistes .alpha.1-adrénergiques, bloqueurs de canal Ca?2+¿ de type L, oestrogènes, activateurs de canal K?+¿ sensible à l'ATP et décontractants musculaires doux.
Lee Charles
Lee Jung-Chung
Mak Vivien
Parks Thomas P.
Cellegy Pharmaceuticals Inc.
Fetherstonhaugh & Co.
Strakan International Limited
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