Compositions and methods for the treatment of bladder cancer

Details Compositions and methods for the treatment of bladder cancer Compositions and methods for the treatment of bladder cancer

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/127 (2006.01) A61K 31/35 (2006.01) A61K 47/20 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2706923

Compositions and methods for the treatment of bladder cancer include intravesical dosage forms of a neoplastic agent and a permeation enhancer. The neoplastic agent may be valrubicin. Pharmaceutical compositions include intravesical dosage forms of a neoplastic agent complexed liposomes. Tight junction openers may be used for the effective delivery of the neoplastic agent.

L'invention porte sur des compositions et procédés destinés au traitement du cancer de la vessie et incluant des formes posologiques intravésicales d'agent antinéoplasique et un stimulateur de pénétration. L'agent antinéoplasique peut être de la valrubicine. Les compositions pharmaceutiques incluent des formes posologiques intravésicales de liposomes incorporant un complexe d'agent antinéoplasique. Des agents d'ouverture de jonctions serrées peuvent être utilisés pour une administration efficace de l'agent antinéoplasique.

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