Compositions and methods for the treatment of colorectal cancer

Details Compositions and methods for the treatment of colorectal cancer Compositions and methods for the treatment of colorectal cancer

A - Human Necessities

61

K

A61K 31/47 (2006.01) A61K 31/445 (2006.01) A61K 31/454 (2006.01) A61K 31/4745 (2006.01) A61K 31/724 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2408710

This invention relates to compositions comprising thalidomide and irinotecan, which can be used in the treatment or prevention of colorectal cancer. The invention also relates to methods of treating or preventing colorectal cancer which comprise the administration of thalidomide and irinotecan to a patient in need of such treatment or prevention. The invention further relates to methods of reducing or avoiding adverse side effects associated with the administration of irinotecan which comprise the administration of thalidomide to a patient in need of such reduction or avoidance.

Cette invention concerne des compositions renfermant de la thalidomide et de l'irinotecan qui peuvent être utilisées pour le traitement ou la prévention du cancer colorectal. L'invention concerne également des méthodes de traitement ou de prévention du cancer colorectal qui consistent à administrer de la thalidomide ou de l'irinotecane à un patient qui en a besoin. De plus, cette invention concerne des méthodes permettant de réduire ou d'éviter les effets secondaires dommageables liés à l'irinotecan, qui consistent à administrer de la thalidomide à un patient chez lequel de tels effets doivent être atténués ou évités.

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