Compositions and methods for the treatment of hepatitis c

Details Compositions and methods for the treatment of hepatitis c Compositions and methods for the treatment of hepatitis c

A - Human Necessities

61

K

A61K 39/295 (2006.01) A61K 39/07 (2006.01) A61K 39/29 (2006.01) A61P 31/04 (2006.01) A61P 31/14 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2731842

Provided are compositions and methods for delivery of one or more hepatitis C virus (HCV) antigens using a bacterium recombinant encoding and expressing such antigens. The bacterial platform comprises the use of attenuated and killed but metabolically active forms of Listeria monocytogenes.

La présente invention concerne des compositions et des procédés d'apport d'un ou de plusieurs antigènes du virus de l'hépatite C (HCV) au moyen d'une bactérie codant pour de tels antigènes de manière recombinante et exprimant ces antigènes. Dans certains modes de réalisation, la plate-forme bactérienne comprend l'utilisation de formes atténuées et tuées mais métaboliquement actives de monocytogènes de Listeria.

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