Compositions and methods for the treatment or prevention of...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01)

Patent

CA 2609467

The invention generally features compositions and methods useful for the treatment and diagnosis of a neoplasia in a subject. In particular, the invention provides therapeutic compositions that decrease the expression of an Nfr2 nucleic acid molecule or polypeptide for the treatment of a neoplasia, such as a chemoresistant neoplasia, in a subject.

L'invention concerne de manière générale des compositions et des procédés utiles pour traiter et diagnostiquer un néoplasme chez un sujet. Elle concerne en particulier des compositions thérapeutiques qui réduisent l'expression d'une molécule d'acide nucléique ou d'un polypeptide de Nfr2 afin de traiter un néoplasme, par exemple un néoplasme chimiorésistant, chez un sujet.

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