Compositions and methods for therapeutic use

Details Compositions and methods for therapeutic use Compositions and methods for therapeutic use

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 38/17 (2006.01) A61K 47/10 (2006.01) A61K 47/16 (2006.01) A61P 35/00 (2006.01) C12N 15/861 (2006.01) C12N 15/87 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2242542

A method and pharmaceutical composition for the treatment of cancer using a gene delivery system, such as a viral vector delivery system, comprising a therapeutic gene such as p53 or a retinoblastoma tumor suppressor gene wherein the gene delivery system is formulated in a buffer comprising a delivery-enhancing agent such as ethanol or a detergent.

L'invention porte sur une méthode et une composition pharmaceutique de traitement du cancer consistant en un système d'apport de gène, par exemple un système d'apport de vecteurs viraux, à base d'un gène thérapeutique tel que le p53 ou d'un gène suppresseur du rétinoblastome. Ledit système est formulé dans un tampon comprenant un agent accélérant l'apport, pouvant être de l'éthanol ou un détergent.

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