C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2660810
The present invention relates to methods which make possible to assess and/or prognose a cancer disease, the metastatic behaviour of a cancer disease and/or the occurrence of a relapse of cancer according to the levels of expression of TPTE and CXCR4. In particular, the methods of the invention make possible to assess and/or prognose the occurrence of cancer metastasis, in particular distant metastasis. Preferably, the methods of the invention allow to discriminate malign from benign conditions.
La présente invention concerne des procédés permettant d'évaluer et/ou de pronostiquer une maladie cancéreuse, le comportement métastasique d'une maladie cancéreuse et/ou l'occurrence d'une rechute de cancer conformément aux taux d'expression de TPTE et CXCR4. En particulier, les procédés de l'invention permettent d'évaluer et/ou de pronostiquer l'occurrence d'une métastase cancéreuse, en particulier une métastase distante. De préférence, les procédés de l'invention permettent de discriminer des conditions malignes et bénignes.
Koslowski Michael
Sahin Ugur
Tuereci Oezlem
Ganymed Pharmaceuticals Ag
Gowling Lafleur Henderson Llp
Johannes Gutenberg-Universitaet Mainz Vertreten Durch Den Praesidenten
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