Compositions and methods for tissue repair with...

A - Human Necessities – 61 – K

Patent

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Details

A61K 35/34 (2006.01) A61P 21/00 (2006.01)

Patent

CA 2741770

Described herein are compositions comprising decellularized cardiac extracellular matrix and therapeutic uses thereof. Methods for treating, repairing or regenerating defective, diseased, damaged or ischemic cells, tissues or organs in a subject, preferably a human, using a decellularized cardiac extracellular matrix of the invention are provided. Methods of preparing cardiomyocyte culture surfaces and culturing cells with absorbed decellularized cardiac extracellular matrix are provided.

L'invention concerne des compositions comprenant une matrice extracellulaire cardiaque décellularisée et des applications thérapeutiques de celles-ci; des méthodes de traitement, de réparation ou de régénération de cellules, de tissus ou d'organes défectueux, pathologiques, endommagés ou ischémiques chez un sujet, de préférence chez l'être humain, à l'aide de la matrice extracellulaire cardiaque décellularisée de l'invention. L'invention concerne des procédés de préparation de surfaces de culture de cardiomyocytes et de culture de cellules utilisant une matrice extracellulaire décellularisée absorbée.

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