A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 9/107 (2006.01) A61K 47/14 (2006.01) A61P 35/00 (2006.01) C07H 21/04 (2006.01)
Patent
CA 2329252
The present invention relates to compositions and methods which enhance the delivery of oligonucleotides and other nucleosidic moieties via topical routes of administration. Preferred compositions include liposomes or penetration enhancers for the delivery of such moieties to dermal and/or epidermal tissue in an animal for investigative, therapeutic or prophylactic purposes.
L'invention concerne des compositions et des méthodes qui permettent d'améliorer l'administration d'oligonucléotides et d'autres fractions nucléosidiques à travers des voies d'administration topique. Des compositions préférées comprennent des liposomes ou des amplificateurs de pénétration permettant d'administrer lesdites fractions aux tissus dermique et/ou épidermique d'un animal à des fins thérapeutiques, prophylactiques ou de recherche scientifique.
Cook Phillip D.
Ecker David J.
Hardee Gregory E.
Mehta Rahul
Templin Michael V.
Isis Pharmaceuticals Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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