C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 38/17 (2006.01) A61P 31/18 (2006.01) C07K 14/435 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2761121
Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
L'invention concerne de nouveaux peptides qui inhibent la libération de microparticules par les cellules. Le peptide contient au moins un motif VGFPV à l'extrémité N-terminale et a une longueur de 10-100 acides aminés. Elle concerne également un polynucléotide qui code le peptide, des vecteurs d'expression portant le polynucléotide et des procédés de traitement du SIDA et de tumeurs au moyen des nouveaux peptides.
Ali Syed
Bond Vincent Craig
Huang Ming Bo
Powell Michael
Raymond Andrea D.
Gowling Lafleur Henderson Llp
Morehouse School Of Medicine
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