Compositions and methods for treating cancer and other...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/14 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2554737

The present invention relates to compositions and methods for treating cancer and other disease states characterized by abnormal cell proliferation. In particular, the present invention relates to certain novel non-nucleoside pharmacologically active compounds that alter telomere and telomerase functions, regulate cell proliferation and/or treat cancer and other diseases characterized by abnormal cell proliferation. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit telomerase, to regulate cell proliferation, and to treat cancer or to inhibit the proliferation of the tumor cells, and to treat other proliferative conditions.

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