C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/30 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2514062
Human IGSF9 and LIV-1 polypeptides and DNA (RNA) encoding such polypeptides are disclosed. The disclosed polypeptides and/or polynucleotide are particularly useful generating antibodies, both modified and native, which bind IGSF9 or LIV-1. Also disclosed are pharmaceutical compositions and vaccines comprising the antibodies, polypeptides and polynucleotides of the invention. Also disclosed are methods for utilizing such polypeptides for identifying ligands, antagonists and agonists to said polypeptides. Finally, methods comprising the above-mentioned compositions are disclosed for the treatment, diagnosis, and/or prognosis of neoplastic disorders.
L'invention concerne des polypeptides humains IGSF9 et LIV-1 ainsi que l'ADN (ARN) codant pour ces polypeptides. Les polypeptides et/ou les polynucléotides selon l'invention conviennent particulièrement pour générer des anticorps, modifiés et natifs, qui se lient à IGSF9 ou à LIV-1. L'invention concerne également des compositions pharmaceutiques et des vaccins comprenant les anticorps, les polypeptides et les polynucléotides selon l'invention. L'invention concerne également des méthodes d'utilisation de ces polypeptides afin d'identifier des ligands, des antagonistes et des agonistes de ces polypeptides. Enfin, l'invention concerne des méthodes comprenant lesdites compositions pour le traitement, le diagnostic et/ou le pronostic des troubles néoplasiques.
Glaser Scott
Mclachlan Karen
Peach Robert J.
Rowe Tony
Biogen Idec Ma Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Compositions and methods for treating cancer using igsf9 and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and methods for treating cancer using igsf9 and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for treating cancer using igsf9 and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1739634