A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2496795
The invention pertains to methods of treating cardiovascular disease by modulating inflammatory and immunoregulatory responses associated with such pathological conditions. Embodiments of the invention provide methods for the treatment of cardiovascular disease in a subject having cardiovascular disease comprising administering an effective amount of one or more IL-17 antagonists, IL-18 antagonists, 4-1BB antagonists, CD30 antagonists, OX40 antagonists and/or CD39 alone or in any combination. This abstract is provided for the sole purpose of enabling the reader to quickly ascertain the subject matter of the technical disclosure and is not intended to be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b).
L'invention porte sur des procédés de traitement de maladies cardio-vasculaires par modulation des réponses inflammatoires et immunorégulatrices associées à de tels états pathologiques. Lesdits procédés consistent à administrer à un patient atteint d'une maladie cardio-vasculaire une dose efficace d'un ou plusieurs antagonistes de l'IL-17, de l'IL-18, du 4-1BB, du CD30, du OX40 et/ou du CD39, seul ou dans toute combinaison possible. Ce résumé a pour seul objet de permettre au lecteur d'identifier rapidement la matière de l'invention, et non d'interpréter ou de limiter l'étendue ou la signification des revendications.
Burton Paul B.
Deisher Theresa A.
Immunex Corporation
Smart & Biggar
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