A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 38/09 (2006.01) A61P 15/00 (2006.01)
Patent
CA 2570960
The present invention is directed to the controlled delivery of gonadotropin- releasing hormone (GnRH) agonists, preferably from a polymeric material that is implanted in the body. More specifically, the present invention relates to compositions comprised of a GnRH agonist, preferably histrelin, in a polymeric material that results in a desired and controlled delivery of a therapeutically effective amount of GnRH agonist over an extended period of time in order to treat central precocious puberty (CPP).
L'invention concerne l'administration commandée d'agonistes d'hormone libérant de la gonadotrophine (GnRH), de préférence à partir d'un matériau polymère implanté dans le corps. Plus précisément, l'invention concerne des compositions comprenant un agoniste GnRH, de préférence de l'histréline, dans un matériau polymère, de manière à obtenir une libération souhaitée et commandée d'une quantité efficace sur le plan thérapeutique de l'agoniste GnRH pendant une durée prolongée, aux fins de traitement de la puberté centrale précoce (CPP).
Borden Ladner Gervais Llp
Endo Pharmaceuticals Solutions Inc.
Valera Pharmaceuticals Inc.
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