A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/405 (2006.01) A61K 31/12 (2006.01) A61K 31/21 (2006.01) A61K 31/221 (2006.01) A61K 31/35 (2006.01) A61K 31/351 (2006.01) A61K 31/40 (2006.01) A61K 31/404 (2006.01) A61K 31/44 (2006.01)
Patent
CA 2335366
The present invention relates to compositions and methods for treating elevated blood cholesterol in a mammal while counteracting the occurrence of potentially adverse side effects such as myopathy. The compositions useful herein comprise the combination of a pharmaceutically effective amount of a 3- hydroxy-3-methylglutaryl coenzyme A reductase inhibitor ("HMG-CoA reductase inhibitor") and a geranylgeraniol compound to a mammal in need thereof.
L'invention concerne des compositions et des méthodes de traitement d'une cholestérolémie élevée chez un mammifère tout en évitant l'apparition d'effets secondaires indésirables tels que la myopathie. Ces compositions contiennent une combinaison d'une dose pharmaceutiquement efficace d'un inhibiteur de la 3-hydroxy-3-méthyl-glutaryle coenzyme A (HMG-CoA) réductase et d'un composé de géranylgéraniol. Ces compositions sont destinées à être administrées à un mammifère nécessitant un tel traitement.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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