Compositions and methods for treating fibroproliferative...

A - Human Necessities – 61 – K

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Details

A61K 31/522 (2006.01) A61K 31/198 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 13/12 (2006.01) A61P 15/00 (2006.01)

Patent

CA 2704100

The present invention relates, in general, to fibroproliferative disorders, and, in particular, to methods and compositions for treating fibroproliferative disorders by administering to a mammal in need of treatment pharmacologically effective doses of a phosphodiesterase inhibitor, such as pentoxifylline, and an anti-oxidant which is a precursor of glutathione, such as N-acetyl-cysteine, or their derivatives or metabolites.

La présente invention concerne, d'une manière générale, les troubles fibroprolifératifs, et, en particulier, des procédés et des compositions permettant de traiter les troubles fibroprolifératifs en administrant à un mammifère ayant besoin de doses de traitement pharmacologiquement efficaces d'un inhibiteur de la phosphodiestérase, tel que la pentoxifylline, et d'un antioxydant qui est un précurseur de la glutathione, tel que la N-acétyl-cystéine, ou leur dérivés ou métabolites.

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